Protein Purification
MilliporeSigma™ Calbiochem™ Vincristine Sulfate, Apocynaceae sp.
Indole alkaloid that binds to tubulin, inhibiting formation of microtubules.
MilliporeSigma™ Calbiochem™ Caspase-1 Inhibitor I
The Caspase-1 Inhibitor I, also referenced under CAS 143313-51-3, controls the biological activity of Caspase-1. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ LY 294002
LY294002, CAS 154447-36-6, is a cell-permeable, potent, reversible, and specific inhibitor of PI 3-kinase ((IC50 = 1.4 μM). Acts on the ATP-binding site.
Thermo Scientific™ CaptureSelect™ Biotin Anti-CD63 Conjugate
Thermo Scientific™ CaptureSelect™ Biotin Anti-CD63 Conjugate consists of a 12–15 kDa recombinant single domain antibody fragment (VHH affinity ligand) that specifically binds with high affinity and selectivity to the tetraspanin marker CD63.
MilliporeSigma™ Calbiochem™ Tranilast
An anthranilic acid analog that acts as a potent inhibitor of VEGF- and vascular permeability factor-induced angiogenesis and collagen synthesis.
MilliporeSigma™ Calbiochem™ (±)-Verapamil, Hydrochloride
A papaverine derivative that blocks Ca2+ channels (principally the L-type) in smooth and cardiac muscle cells.
MilliporeSigma™ Calbiochem™ Glucokinase Activator II
A cell-permeable compound that reduces glucokinase Km for glucose (EC50 = 120 nM & 350 nM, for human and rat enzyme). Enhances insulin secretion from INS-1 cells upon glucose exposure.
MilliporeSigma™ Calbiochem™ Nef Hck Activation Inhibitor, B9
A cell-permeable diphenylpyrazolo compound that disrupts HIV accessary protein Nef dimerization (IC50 = 3μM in HEK293T cells) and prevents Nef-mediated Src family kinase Hck activation (IC50 )
MilliporeSigma™ Calbiochem™ BEC, Hydrochloride
A boronic acid-based arginine analog that acts as a slow-binding, competitive transition state inhibitor of arginases I and II (Ki = 310 nM for human recombinant type II arginase, pH 7.5).
MilliporeSigma™ Calbiochem™ α-Synuclein Blocker, ELN484228
A cell-permeable compound that reversibly binds to pocket I of the monomeric α-synuclein (α-syn) and reverses α-syn-induced impairment of phagocytosis in H4 neuroglioma cells.
MilliporeSigma™ Calbiochem™ eIF4E/eIF4G Interaction Inhibitor II, 4E1RCat
The eIF4E/eIF4G Interaction Inhibitor II, 4E1RCat controls the biological activity of eIF4E/eIF4G interaction. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ SHIP1 Inhibitor, 3AC
The SHIP1 Inhibitor, 3AC controls the biological activity of SHIP1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ α-Naphthyl Acid Phosphate, Monosodium Salt
α-Naphthyl Acid Phosphate, Monosodium Salt - CAS 81012-89-7, is a broad-spectrum protein phosphatase inhibitor.
MilliporeSigma™ Calbiochem™ MLKL Inhibitor, Necrosulfonamide
MLKL Inhibitor, Necrosulfonamide, CAS 432531-71-0, is a cell-permeable inhibitor that covalently modifies Cys88 and blocks human MLKL adaptor function.
MilliporeSigma™ Calbiochem™ MG-132, ≥95% by HPLC
Potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM).